Cash and jewellery were stolen from a Thame home yesterday (Monday).
The home in Chowns Close was burgled at about 1pm.
Police are keen to speak to anyone who may have seen two men hanging around the area before 1pm or running off following the burglary.
The first man is white, aged around 40, of large build and around 5ft 10ins with dark hair.
He was casually dressed in a light grey hooded top and jogging bottoms.
The second man is white, aged around 18 to 20, of slim build and is around 5ft 10ins.
He was wearing a dark woolly hat and dark clothes.
Anyone with information should call police on 101 and ask to speak to Det Con Stephen Knight.
Alternatively you can call Crimestoppers anonymously on 0800 555 111.