More than £1500 has been raised through a street collection, open gardens and Pimms afternoon.
Sue and Byron Harvey, from Wellington Street, held the event to raise funds for the charity Dogs for the Disabled.
There was also a tombola stall, a homemade cake stall and a raffle.
The couple, who are both disabled, raised £377.17 from a two-hour street collection and £1132.20 from the open gardens.
Sue said: “We would like to thank everyone who so tirelessly supported us with this fundraiser.
“We would like to thank the people of Thame for helping us to raise this vast amount and we thank all the people who came and helped because we couldn’t do this on our own.”
The couple, who are both paraplegic rely on two working dogs, Max and Ziggy to help them complete everyday tasks.
These include getting undressed, turning the washing machine off and emptying shopping baskets.